Natural Prostate Protection: Herbs, Antioxidants & Essential Nutrients Guide 2025

Natural Prostate Protection featured image

Summary:

  • Natural compounds like saw palmetto and pygeum show proven results in supporting prostate health within 3-6 months.
  • Specific antioxidants, especially lycopene from cooked tomatoes, provide powerful protection against prostate inflammation.
  • Combining key nutrients like omega-3s, zinc, and selenium creates a comprehensive shield for prostate health.
  • Strategic lifestyle changes, including Mediterranean diet and proper hydration, significantly enhance prostate protection.
  • Regular monitoring and medical supervision ensure optimal results from natural prostate protection methods.

Your Guide to Natural Prostate Protection

Did you know that a staggering 9 out of 10 men will face prostate issues by age 85? 

I remember when I first discovered this statistic – it completely changed my approach to prostate health research and natural protection methods.

The quest for effective natural prostate protection has become more crucial than ever. 

Through my learning from leading institutions in London and Cambridge, I’ve uncovered powerful combinations of herbs, antioxidants, and essential nutrients that work synergistically to support prostate health.

“There is plenty of strong evidence that good nutrition and an active lifestyle can reduce the likelihood of prostate cancer and slow its progression.”

Mitchell Sokoloff M.D., Chair of the Department of Urology at the University of Massachusetts Medical School.

My background in biochemistry has helped me understand how these natural compounds interact with prostate tissue. 

What’s truly exciting is seeing how simple changes in diet and lifestyle, combined with specific natural supplements, can create a robust shield for prostate health.

At ProstaKnight, I lead a dedicated team committed to bringing you the most effective, science-backed strategies for natural prostate protection.

Key Points:

Herbal PowerNatural herbs like saw palmetto and pygeum work synergistically to reduce prostate inflammation and improve urinary function when used consistently.
Nutrient SynergyThe combination of specific antioxidants, minerals, and omega-3s creates a comprehensive protective shield for optimal prostate health.
Lifestyle IntegrationStrategic timing of supplements, proper hydration, and Mediterranean diet principles maximize the benefits of natural prostate protection.
Quality MattersThird-party tested supplements and medical supervision ensure safe, effective implementation of natural prostate protection methods.

Table of Contents:

1. Understanding Natural Prostate Protection Basics

Essential Functions of the Prostate Gland 

It never ceases to amaze me how this small walnut-sized gland plays such a vital role in men’s health. 

The prostate’s primary function is producing the milky fluid that nourishes and protects sperm, making up about 30% of a man’s seminal fluid.1

Think of it as a natural gateway that helps regulate both reproductive and urinary functions.

Common Concerns Affecting Men 

Let me share something that often surprises people: by age 60, about 50% of men will experience some form of prostate issue and by age 85, the proportion reaches 90%.2

The three most significant concerns I encounter are:

  • Benign Prostatic Hyperplasia (BPH) – prostate enlargement that affects urination
  • Prostatitis – inflammation that can cause discomfort
  • Prostate cancer – affects 1 in 8 men during their lifetime

Why Natural Protection Methods are Gaining Popularity 

I’ve noticed a significant shift in how men approach prostate health over the past decade. 

More patients are seeking natural solutions before turning to conventional medications, and for good reason.

Natural methods often come with fewer side effects and can be used preventatively. 

The rising interest in holistic health has also led to more research backing these natural approaches.

Table: Natural Prostate Protection Methods Comparison

Protection MethodOnset TimeEffectivenessSide EffectsCost Effectiveness
Herbal Supplements3-6 monthsHighMinimalModerate
Antioxidants2-4 monthsModerate-HighVery LowHigh
Dietary Changes1-3 monthsModerateNoneVery High
Lifestyle Modifications1-2 monthsHighNoneHigh
Combined Approach2-4 monthsVery HighMinimalHigh
This comprehensive comparison table helps understand the various aspects of different natural prostate protection methods, including their timeline for results, effectiveness, potential side effects, and cost considerations.

Role of Inflammation in Prostate Health 

I’ve learned that inflammation is often the hidden culprit behind many prostate issues. It’s like a silent troublemaker that can lead to various prostate problems if left unchecked.

Chronic inflammation can trigger prostate cell growth and potentially lead to enlargement or other complications. 

This is why anti-inflammatory approaches are crucial in natural prostate protection.

Natural vs Conventional Approaches to Prostate Care 

From what I’ve observed, the best approach is often a balanced one. 

While conventional treatments focus on symptom management, natural methods typically aim to address underlying causes.

Here’s how they compare:

Natural Approaches:

  • Focus on prevention
  • Support overall prostate health
  • Minimal side effects
  • Gradual improvements
  • May require lifestyle changes

Conventional Approaches:

  • Rapid symptom relief
  • Medically monitored
  • Possible side effects
  • Usually prescription-based
  • Often treat specific conditions
Think about this:
"The key to prostate health isn't just treating symptoms when they arise – it's creating an environment where your prostate can thrive naturally through preventive care and protection."

Consider combining both natural and conventional approaches under medical supervision for optimal results. 

Natural protection methods can work alongside traditional treatments, creating a comprehensive shield for your prostate health.

2. Powerful Herbs for Prostate Health

Saw Palmetto’s Role in Prostate Protection 

Maybe, it’s just me, but I’ve found saw palmetto to be one of the most effective herbs for prostate health. 

This palm plant native to the southeastern United States works by inhibiting 5-alpha-reductase, the enzyme that converts testosterone to DHT.3

“Because DHT is also involved in the enlargement of the prostate gland, decreasing your levels of DHT by using saw palmetto may also improve4 prostate health and BPH.”

healthline

What makes saw palmetto particularly interesting is its dual action – it not only helps reduce prostate inflammation but also decreases the number of estrogen and androgen receptors. 

Benefits of Pygeum Africanum Extract 

The bark of the African plum tree has been superb for many people. 

Pygeum africanum contains unique compounds that act as powerful antioxidants and anti-inflammatories specifically targeting the urogenital system.

It has been observed that men taking pygeum often report improved urinary flow and reduced nighttime bathroom visits. 

However, I always emphasize sustainable sourcing, as this resource needs protection.

Stinging Nettle Root Properties 

Stinging nettle might sound intimidating, but its benefits for prostate health are impressive. 

Many doctors talk about the particularly good results when combining it with saw palmetto, as they work synergistically.

The anti-inflammatory compounds in nettle root help reduce prostate size and improve urinary symptoms. 

Rye Grass Pollen Extract Effectiveness 

Rye grass pollen extract has shown promising results, particularly for men with prostate inflammation. 

It helps reduce prostate size and improve urinary symptoms through its anti-inflammatory properties.

Natural prostate protection herbs

Proper Dosage and Usage Guidelines 

From my experience, proper dosing is crucial for achieving optimal results in my loved ones. 

I recommend starting with lower doses and gradually increasing them based on individual responses.

HerbActive CompoundsPrimary BenefitsDaily Dosage
Saw PalmettoBeta-sitosterol, Fatty acidsDHT reduction, Anti-inflammatory320mg
PygeumPhytosterols, Pentacyclic triterpenesUrinary flow improvement75-200mg for 12 months
Stinging NettleLignans, PolysaccharidesProstate size reduction120-360mg for 6 months
Rye Grass PollenBeta-sitosterol, PhytosterolsInflammation reduction126mg for 24 weeks
Note: Consulting with a medical professional is recommended before adding these dosages to your diet to make sure they are tailored to your body's specific needs.
Think about this:
"Success with herbal remedies comes from consistency and patience – these natural solutions work gradually but can provide sustainable, long-term prostate health benefits."

3 Essential Antioxidants and Their Protective Effects

Lycopene-Rich Foods and Supplements 

Based on my research, lycopene stands out as a powerhouse antioxidant for prostate health. 

What’s fascinating is how cooking actually increases its bioavailability – I always tell people that cooked tomato products are far more effective than raw ones.

The research professionals reviewed shows that men who consume more lycopene-rich foods have better prostate health outcomes.5 The best sources I recommend include:

  • Cooked tomato products (sauce, paste, juice)
  • Watermelon
  • Pink grapefruit
  • Red bell peppers
  • Papaya

Green Tea Polyphenols Benefits 

I’ve seen studies in patients who incorporate green tea into their daily routine. 

The polyphenols, especially EGCG, work as powerful antioxidants that specifically target prostate tissue.

What’s particularly interesting is how these compounds help regulate prostate cell growth and reduce the risk of prostate cancer. 6

I often see experts recommend drinking 3-4 cups daily for optimal benefits.7

However, you should check with your doctor before incorporating green tea into your diet. The Georgia Prostate Institute says men who already have BPH might find their symptoms aggravated by drinking caffeinated beverages such as black and green tea.8

Role of Selenium in Prostate Health 

A 2018 study shows that selenium plays a protective role against the development of prostate cancer.9

It’s not just about taking supplements – I emphasize getting selenium through whole food sources whenever possible as well.

Key selenium sources I recommend:

  • Brazil nuts (just 1-2 daily meets requirements)
  • Seafood
  • Organ meats
  • Sunflower seeds

Zinc’s Protective Properties 

My studies have shown that zinc deficiency often correlates with prostate issues, especially in men over 50. 10

What’s crucial to understand is that zinc uptake decreases with age, making supplementation more important as we get older.

I’ve found these zinc-rich foods to be particularly beneficial:

  • Pumpkin seeds
  • Oysters
  • Grass-fed beef
  • Lentils

Optimal Antioxidant Combinations 

I’ve learned that combining these antioxidants creates a synergistic effect. The key is strategic timing and proper combinations for maximum absorption.

My recommended daily antioxidant stack:

  • Morning: Green tea with breakfast
  • Lunch: Lycopene-rich foods cooked in healthy fats
  • Dinner: Zinc-rich proteins with selenium-containing sides
  • Throughout day: Colorful fruits and vegetables
Think about this:
"The power of antioxidants lies not just in their individual benefits, but in their synchronized action – like an orchestra playing in perfect harmony to protect your prostate health."

Table of Antioxidant Sources and Benefits:

AntioxidantFood SourcesDaily TargetBenefits for Prostate
LycopeneTomato products, Watermelon10-30mgCell protection, PSA reduction
Green Tea PolyphenolsGreen tea3-4 cupsAnti-inflammatory, Growth regulation
SeleniumBrazil nuts, Seafood55-70mcgDNA protection, Immune support
ZincPumpkin seeds, Oysters11mgHormone balance, Cell health
This table shows the dosages of the antioxidants for daily use and the benefits derived.
Note: It’s advisable to consult with a medical professional before incorporating these antioxidants into your diet to ensure you’re getting the most beneficial dosage tailored to your body’s needs.

4. Bioflavonoid Properties and Active Compounds

Understanding Bioflavonoid Mechanisms 

Through my research in phytonutrients, I’ve discovered that bioflavonoids are truly remarkable in their prostate-protective abilities. 

These plant-based compounds work through multiple pathways, primarily by reducing oxidative stress and modulating inflammatory responses.

I believe these compounds act as natural defense shields for prostate cells. 

They work similarly to your body’s own antioxidant systems, but provide additional support where it’s needed most.

Key prostate-protective compounds, certain bioflavonoids stand out for prostate health:

  • Quercetin
    • powerful anti-inflammatory properties11
    • stops the growth and causes the death of prostate cancer cells without affecting normal prostate cells.12
  • Rutin
    • strengthens blood vessel walls and lowers cholesterol13
    • stops the growth of cancer cells14
  • Hesperidin
    • supports cellular health15
    • improves blood circulation and reduces inflammation16
  • Apigenin
    • helps regulate cell growth17
    • slows down the progression of prostate cancer18

These compounds work together to create what I call a “protective matrix” around prostate tissue.

Synergistic Effects with Other Nutrients 

What fascinates me most is how bioflavonoids enhance the effectiveness of other nutrients. I’ve been told that when combined with vitamin C, their absorption and effectiveness increase significantly.

The synergistic relationships I’ve found most beneficial include:

  • Bioflavonoids + Vitamin C
  • Quercetin + Zinc
  • Rutin + Selenium
  • Hesperidin + Vitamin E
BioflavonoidPrimary SourceMain BenefitSynergistic Partner
QuercetinOnions, ApplesAnti-inflammatoryZinc
RutinCitrus fruitsVascular healthSelenium
HesperidinOrange peelCell protectionVitamin E
ApigeninParsley, CeleryGrowth regulationVitamin C

Absorption and Bioavailability Factors 

I’ve learned that absorption is crucial for effectiveness. Bioavailability varies significantly depending on several factors:

  • Form of supplement (liposomal forms show better absorption)
  • Timing of intake (best taken with meals)
  • Combination with healthy fats
  • Individual digestive health

Research-Backed Benefits 

I see that you can have consistent benefits when bioflavonoids are properly absorbed:

  • Reduced prostate inflammation
  • Better urinary flow
  • Decreased oxidative stress
  • Improved prostate cell health
  • Enhanced nutrient delivery to prostate tissue
Think about this:
"Bioflavonoids act as nature's molecular architects, carefully rebuilding and maintaining prostate health at the cellular level."

5. Critical Nutrients for Prostate Protection

Omega-3 Fatty Acids Importance 

I’ve found that omega-3 fatty acids are crucial for prostate health. 

These essential fats help reduce inflammation at the cellular level, something experts consistently observed in their clinical work.

I recommend focusing on these specific sources:

  • Cold-water fatty fish (salmon, mackerel, tuna, sardines)
  • Flaxseeds and chia seeds
  • Walnuts
  • High-quality fish oil supplements

However, I should make known that there was a study back in 2013 that found a link between higher levels of omega-3 fatty acids in the blood and an increased risk of prostate cancer,19 but it didn’t prove that omega-3s (like those from fish oil) cause prostate cancer. In fact, it seems to lower the chance of dying from prostate cancer and significantly reduces the risk of sudden death and heart-related events.20

Vitamin D and Prostate Health 

Vitamin D isn’t just for bone health – it’s a critical player in prostate protection. 

Living in areas with less sun exposure, I’ve noticed many studies that men are deficient in this crucial nutrient.

Key aspects of vitamin D for prostate health:

  • Supports immune function
  • Regulates cell growth
  • Reduces inflammation
  • Improves nutrient absorption

Essential Minerals Overview 

Obviously, I see certain minerals are absolute must-haves for prostate health. 

The synergy between these minerals creates what I call a “mineral shield” for the prostate.

Critical minerals I recommend monitoring:

  • Selenium (55-70 mcg daily)
  • Zinc (11-15 mg daily)
  • Magnesium (400-420 mg daily)
  • Boron (3-6 mg daily)
Note: It’s advisable to consult with a medical professional before incorporating these minerals into your diet to ensure you get the most beneficial dosage tailored to your body’s needs.

Beta-sitosterol Benefits 

There are remarkable improvements in patients using beta-sitosterol, a plant sterol that naturally supports prostate function. 

It’s fascinating how this compound improves urinary flow and symptoms. It improves BPH symptoms as well but does not shrink an enlarged prostate.21

Best natural sources include:

  • Pumpkin seeds
  • Avocados
  • Pistachios
  • Olive oil

Based on my studies, proper dosing is crucial. 

Daily nutrient targets:

  • Omega-3s: 1,000-2,000 mg EPA/DHA combined
  • Vitamin D: 2,000-4,000 IU (with regular blood level monitoring)
  • Beta-sitosterol: 60-130 mg
  • Combined minerals: Based on individual needs and current levels
Note: It’s advisable to consult with a medical professional before incorporating these minerals into your diet to ensure you get the most beneficial dosage tailored to your body’s needs.

6. Lifestyle Factors for Enhanced Protection

Anti-Inflammatory Diet Guidelines 

I’ve found that an anti-inflammatory diet forms the cornerstone of prostate protection. 

The Mediterranean diet pattern has consistently shown some really promising results in my opinion.

Key dietary principles I recommend:

  • Emphasis on colorful vegetables and fruits
  • Limited red meat consumption
  • Healthy fats from olive oil and fish
  • Minimal processed foods and added sugars
  • Regular consumption of cruciferous vegetables

Exercise Recommendations 

Physical activity isn’t just good for overall health – it’s crucial for prostate protection. 

A lot of men who maintain regular exercise routines often have better prostate health outcomes.

Most effective exercise types I’ve found:

  • Moderate aerobic activity (30 minutes daily)
  • Regular walking (especially after meals)
  • Kegel exercises for pelvic floor strength
  • Light resistance training
  • Yoga or stretching for circulation

Stress Management Techniques 

What many don’t realize is how significantly stress impacts prostate health. 

I think anyone can see that Chronic stress can exacerbate prostate issues through increased inflammation.

Effective stress-reduction strategies:

  • Daily meditation (even 10 minutes helps)
  • Deep breathing exercises
  • Regular nature walks
  • Mindfulness practices
  • Social connection and support

Sleep Optimization Strategies 

Quality sleep is non-negotiable for prostate health. Poor sleep patterns can disrupt hormonal balance and increase inflammation.

Key sleep strategies I recommend:

  • Consistent sleep schedule
  • Dark, cool bedroom environment
  • Limited fluid intake before bed
  • No screen time 1 hour before sleep
  • Relaxation routine before bedtime

Hydration Importance 

I’ve found that proper hydration plays a vital role in prostate health, though many men fear drinking enough water due to urinary symptoms. The key is timing your fluid intake strategically.

I do have some hydration guidelines, but always check with your health care provider for sure:

  • 2-3 liters of water daily
  • More fluids in morning and afternoon
  • Reduced intake after 6 PM
  • Herbal teas as beneficial alternatives
  • Monitoring urine color for hydration status
Think about this:
"Lifestyle changes aren't just about preventing problems – they're about creating an environment where your prostate can thrive naturally and maintain optimal function."
Lifestyle FactorDaily GoalsBenefitsTiming
Anti-inflammatory Diet7-9 servings vegetablesReduced inflammationThroughout day
Exercise30 minutes moderate activityBetter circulationMorning/afternoon
Stress Management10-20 minutes meditationHormonal balanceAny time
Sleep7-9 hours quality restRecovery & repair10 PM – 6 AM
Hydration2-3 liters of waterOptimal functionBefore 6 PM
Lifestyle Factors to improve prostate health

7. Pros of Natural Prostate Protection

Natural prostate protection isn’t just about preventing problems – it’s about optimizing your body’s innate ability to maintain and repair itself.

Benefit CategoryShort-term GainsLong-term ImpactSupporting Evidence
EffectivenessSymptom reliefDisease preventionClinical studies
Side EffectsMinimal disruptionBetter complianceSafety records
PreventionEarly protectionReduced riskLong-term studies
CostReasonable investmentHealthcare savingsEconomic analysis
Holistic HealthMultiple benefitsOverall wellnessQuality of life data

8. Cons and Considerations

Time Required for Visible Results 

From my experience, I’ve learned that patience is crucial when using natural approaches. 

Unlike pharmaceutical options, natural methods typically take time to show their full benefits.

The path to natural prostate health isn’t always straightforward – it’s about finding the right balance between effectiveness, safety, and individual needs.

Importance of Medical Supervision 

Based on my experience, successful natural prostate protection requires proper medical oversight

Regular monitoring ensures safety and allows for timely adjustments to the protocol.

Table of Risk Level, Strategy, and Importance of Monitoring:

ConsiderationRisk LevelMitigation StrategyMonitoring Need
Time FactorLowPatient educationMonthly tracking
Supplement QualityModerateThird-party testingBrand verification
Drug InteractionsHighMedical disclosureRegular review
Individual ResponseModeratePersonalized approachSymptom tracking
Medical OversightEssentialRegular check-upsQuarterly visits

Taking Action for Your Prostate Health

From powerful herbs like saw palmetto to essential antioxidants and critical nutrients, I’ve shared my most valuable insights from decades of research and observation.

The beauty of natural protection lies in its comprehensive approach. 

It’s not just about taking supplements – it’s about creating an environment where your prostate can thrive naturally. 

The synergy between different natural compounds, combined with lifestyle modifications, creates a powerful shield for long-term prostate health.

Start small – perhaps with diet modifications or a single supplement. 

Monitor how your body responds. Build your natural protection strategy gradually, always keeping in touch with your healthcare provider.

Your prostate health journey is unique to you. Trust your body, listen to its signals, and give natural methods the time they need to work their magic. 

The path to optimal prostate health is a pretty patient one- but with these natural tools at your disposal, you’re well-equipped for the journey ahead.

Frequently Asked Questions

How long until I see results?

Natural prostate protection methods typically show initial improvements within 4-8 weeks. 

I’ve seen studies where most men notice significant changes in urinary symptoms and overall prostate health within 3-6 months of consistent use of herbs, antioxidants, and lifestyle modifications.

Which herbs work best?

Saw palmetto and pygeum are the most effective herbs for prostate protection to me. 

I’ve seen remarkable results when these are combined with stinging nettle and rye grass pollen extract, particularly for reducing prostate inflammation and improving urinary flow.

Are natural supplements safe?

Natural prostate protection supplements are generally safe when properly sourced and dosed. 

However, I always emphasize the importance of choosing high-quality products and consulting with healthcare providers, especially if you’re taking other medications.

Do I need medical supervision?

Yes, regular medical oversight is crucial for natural prostate protection. I recommend quarterly check-ups and PSA testing to monitor progress and ensure your natural protocol is working effectively.

What foods help most?

From my research, lycopene-rich foods like cooked tomatoes, along with foods high in omega-3s such as fatty fish, provide the strongest prostate protection. 

I’ve seen significant improvements in people who follow a Mediterranean-style diet rich in these foods.

Which antioxidants are essential?

Lycopene, selenium, and green tea polyphenols are the most crucial antioxidants for prostate health. 

I’ve found that combining these with zinc and vitamin D creates the most effective antioxidant shield for the prostate.

Ready to take control of your prostate health naturally? Start with one simple change today – your prostate will thank you!

Resources:

  1. Lawrentschuk N, Ptasznik G, Ong S. Benign Prostate Disorders. [Updated 2021 Oct 7]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. ↩︎
  2. The growing problem of an enlarged prostate gland. [2024 Aug 10].[Internet]. Harvard Health Publishing ↩︎
  3. Pais P. Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5alpha-reductase II. Adv Ther. 2010 Aug;27. ↩︎
  4. Kim EH, Brockman JA, Andriole GL. The use of 5-alpha reductase inhibitors in the treatment of benign prostatic hyperplasia. Asian J Urol. 2018 Jan;5(1):28-32. Epub 2017 Nov 26. ↩︎
  5. Holzapfel NP, Holzapfel BM, Champ S, Feldthusen J, Clements J, Hutmacher DW. The potential role of lycopene for the prevention and therapy of prostate cancer: from molecular mechanisms to clinical evidence. Int J Mol Sci. 2013 Jul 12;14(7):14620-46. ↩︎
  6. Johnson JJ, Bailey HH, Mukhtar H. Green tea polyphenols for prostate cancer chemoprevention: a translational perspective. Phytomedicine. 2010 Jan;17(1):3-13. ↩︎
  7. The best drink for your enlarged prostate ↩︎
  8. Should You Drink Tea for Prostate Health? ↩︎
  9. Sayehmiri K, Azami M, Mohammadi Y, Soleymani A, Tardeh Z. The association between Selenium and Prostate Cancer: a Systematic Review and Meta-Analysis. Asian Pac J Cancer Prev. 2018 Jun 25;19(6):1431-1437. ↩︎
  10. Sauer AK, Vela H, Vela G, Stark P, Barrera-Juarez E, Grabrucker AM. Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders. Front Oncol. 2020 Aug 6;10:1293. ↩︎
  11. Lotfi N, Yousefi Z, Golabi M, Khalilian P, Ghezelbash B, Montazeri M, Shams MH, Baghbadorani PZ, Eskandari N. The potential anti-cancer effects of quercetin on blood, prostate and lung cancers: An update. Front Immunol. 2023 Feb 28;14:1077531. ↩︎
  12. Aalinkeel R, Bindukumar B, Reynolds JL, Sykes DE, Mahajan SD, Chadha KC, Schwartz SA. The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90. Prostate. 2008 Dec 1;68(16):1773-89. ↩︎
  13. The Potential Health Benefits of Rutin ↩︎
  14. Satari A, Ghasemi S, Habtemariam S, Asgharian S, Lorigooini Z. Rutin: A Flavonoid as an Effective Sensitizer for Anticancer Therapy; Insights into Multifaceted Mechanisms and Applicability for Combination Therapy. Evid Based Complement Alternat Med. 2021 Aug 23;2021:9913179. ↩︎
  15. Jeong SA, Yang C, Song J, Song G, Jeong W, Lim W. Hesperidin Suppresses the Proliferation of Prostate Cancer Cells by Inducing Oxidative Stress and Disrupting Ca2+ Homeostasis. Antioxidants (Basel). 2022 Aug 23;11(9):1633. ↩︎
  16. Hesperidin – Uses, Side Effects, and More ↩︎
  17. Allemailem KS, Almatroudi A, Alharbi HOA, AlSuhaymi N, Alsugoor MH, Aldakheel FM, Khan AA, Rahmani AH. Apigenin: A Bioflavonoid with a Promising Role in Disease Prevention and Treatment. Biomedicines. 2024 Jun 18;12(6):1353. ↩︎
  18. Shukla S, Bhaskaran N, Babcook MA, Fu P, Maclennan GT, Gupta S. Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway. Carcinogenesis. 2014 Feb;35(2):452-60. ↩︎
  19. Brasky TM, Darke AK, Song X, Tangen CM, Goodman PJ, Thompson IM, Meyskens FL Jr, Goodman GE, Minasian LM, Parnes HL, Klein EA, Kristal AR. Plasma phospholipid fatty acids and prostate cancer risk in the SELECT trial. J Natl Cancer Inst. 2013 Aug 7;105(15):1132-41. ↩︎
  20. DiNicolantonio JJ, McCarty MF, Lavie CJ, O’Keefe JH. Do omega-3 fatty acids cause prostate cancer? Mo Med. 2013 Jul-Aug;110(4):293-5. ↩︎
  21. Benign prostatic hyperplasia ↩︎

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